COVID19: helping ourselves

The first reported case of COVID 19 was found almost more than a year ago in China; since then, multiple other strains have been discovered. Despite major nations declaring the vaccines' success against the virus; it is hampering the countries with increasing numbers of infections. There is a hope of a possible end to the pandemic since rolling out the vaccination programmes, but vaccines' efficacy has yet to impact the infection rate. There are no active treatments as yet if you get infected by COVID19.

Advice from the government and NHS has largely centred around preventative methods. However, there is no clear or little advice on improving your immune functions to fight against the virus and avoid complications associated with COVID19 if you get infected.

This is my advice after researching how we can improve our immune system if you get infected with COVID19.


As soon as you develop any of the symptoms that could be of COVID19

  • Cough
  • Fever
  • Headache
  • New loss of taste or smell
  • Repeated shaking with chills
  • Sore throat
  • Shortness of breath
  • Muscle pain

Please do take vitamins, minerals, enzymes and keep hydrated

1) Vitamins
a. Vitamin D higher doses up to 20000IU a day for at least fourteen days if you have not taken any vitamin D supplements; If you have taken at least 1000IU              regularly, please take 10000IU daily for two weeks.
b. Vitamin C 500mg every six hours for two weeks.

2) Minerals
a. Magnesium up to 250 mg twice a day.
b. Zinc 25 mg twice a day.

3) Enzymes
a. Coenzyme Q10 300mg a day.
b. Bromelain 500mg four times a day if you are not on any blood-thinning medications.

4) Keep your self well hydrated with warm water

5) Keep active within your limitations

There are numerous reports on the association of the severity of COVID19 in conjunction with low levels of vitamin and minerals. Deficiencies of vitamins and minerals could be due to the disease state's enhanced requirement or could be due to chronic dietary insufficiency. These vitamins and minerals are essential in normal cellular homeostasis and for the host immune response. The cellular biological mechanisms are extraordinarily complex, and the cells need mineral and vitamins to function in optimum levels. Most of the biological mechanisms are interconnected, reliant on several steps of vitamins, enzymes, and cofactors activities. The dysfunction of one of the cellular biochemical function can lead to inefficiency of the entire cell function. Therefore enhancing the vitamin and mineral intake during this season will help you to improve your immunity and fight against it.



Why Vitamin D?

The vast number of physiological effects of vitamin D facilitates activating the Vitamin D receptors (VDR) signalling pathway to generate many beneficial effects. Stimulation of the VDR leads adjusts the cytokines and chemokines activity, the renin-angiotensin systems, and the neutrophil activity. These activities help to maintain
the pulmonary epithelial barrier integrity, stimulate the epithelial repair, and down-regulate the increase coagulation, preventing ARDS. Most UK adults are low in vitamin D; therefore, you need to take high doses of Vitamin D to improve the levels. If you are a man or a woman with an average body weight around 70 Kg with Body mass index (BMI) less than 30, you can take vitamin D 3 20000IU daily for few weeks without having any side effects but not for the long term. There are no recorded side effects of supplementing Vitamin D3 20,000 IU for two weeks, and the 20000 IU dose is more physiological. It will enable to boost the serum vitamin D levels.

How much of Vitamin D should I take if I have never taken vitamin D supplements before?

You should take up to 20000 IU for at least few weeks then continue at the lower dosage. This allows the body to saturate with vitamin D3.

What are the side effects of vitamin D3?

There are no recorded severe risks in short term intake of high dosage of Vitamin D3. In my experience, the most common symptoms of high vitamin D intake are that
you may feel headaches, bloated tummy and increase gas. These side effects can avoid by hydrating the body.

Can the Vitamin D3 cause kidney stones as one of the significant functions of Vitamin D3 is absorbing calcium?

Kidney stones formation is overly complicated, and it is exceedingly rare only due to Vitamin D3. You can avoid the risks by appropriately hydrating your body. If your kidney functions are not normal, you should seek advice from your doctors.



What are the beneficial effects of Vitamin C in COVID 19?

Vitamin C's beneficial effects are known for generations and regular supplementation of higher doses found to be efficacious to reduce the duration of the cold. The antiviral effects of vitamin C modulated through hydrogen peroxide and other free radicals production that may be harmful to the virus. Vitamin C is a potent antioxidant which directly scavenges some of the free radicals produce during the infections, and it is, therefore, may restore the viral induce lung injury.

How much of Vitamin C, should I take?

Vitamin C is water-soluble, and the availability in the blood depends on gut absorption and excretion through the kidneys. There are recommendations to take very high doses to reduce cold, but the high dosed can irritate the stomach; therefore, I recommend taking 500mg six hourly for two weeks.

Are there any side effects of Vitamin C?

There are no reported side effects of oral vitamin C intake other than mild gastric irritations when taking more than 2g a day. These side effects could be reduced by
taking chewable Vitamin C and absorb well. You will be able to get the highest recommended highest dose (2g) a day, in smaller doses (500mg) by taking up to four times a day to keep the vitamin C blood levels within an optimum level during the infections. Only the people who have G6PD hormone deficiency should take a lower vitamin C dose. Still, there are no records of any complications by taking the oral form of vitamin C at these doses.



What are the benefits of Zinc in COVID-19?

Zinc is an essential micronutrient to all living organisms and participates in numerous biochemical activities. The Zinc plays an integral part in maintaining human health
by cellular enzyme activations, maintaining proteins' structural integrity, and regulating ion channel activity. Zinc deficiency is associated with altered cell numbers and dysfunction of all levels of immune cells. The subjects with sub-optimum zinc levels found to have increase risks of diseases. The optimum Zinc levels protect the human body from entering viruses, inhibits the viral replications, and balances the immune response during infections.

How much Zinc should I take?

The requirement of Zinc is about 25mg a day for regular intake. If you feel you get any symptoms of COVID19, we recommend taking 25 mg twice a day for two weeks.

What are the side effects of Zinc?

The Zinc supplements are safe to take and useful to improve body zinc levels; nevertheless in long term intake more than 200mg a day, can cause feeling nauseous, vomiting, diarrhoea, stomach cramps.



What are the benefits of Magnesium?

The Magnesium is an alkaline metal and the second most important mineral found in all tissues, and 99% of Magnesium remained in the in cells. The Magnesium is vital in protein synthesis, and in every metabolic function involving the creation of energy and its transport. The Magnesium is essential to convert vitamin D to its metabolically active form. The body does not retain Magnesium, and its deficiency is widespread and integrally involved in so many diseases. The prevalence of hypomagnesemia ranges from 9 to 65%, and the deficit is highly likely in severely sick patients.

How much Magnesium should I take?

As magnesium deficiency is very high in the community, you may have low Magnesium levels with the infection. I would recommend taking up to 500 mg of Magnesium a day for two weeks.

What are the side effects of Magnesium?

Your intestine and kidneys excrete extra Magnesium you take. It is exceedingly rare to have a high level of Magnesium in your blood at this level of short-term supplementation. If you are known to have low kidney functions, supplements may cause an increase in magnesium levels. You may not have any symptoms unless your blood magnesium levels are significantly elevated. If so, you may feel nausea, vomiting, muscle weakness, confusion, decreased reflexes and palpitations.



What is the benefits of Co-enzyme Q 10 in Covid19?

Coenzyme Q-10 (CoQ10) is an antioxidant that occurs naturally in the body. It's also known as ubiquinone; its central role is an integral part of the mitochondrial respiratory chain for energy production. The mitochondrial function can impair in severe infections and may produce less energy unit for the cell. The CoQ-10 also has a role in antioxidant function, inhibitions of circulating low- density lipoproteins (LDL), and inhibition of membrane lipid oxidation and improving endothelial function by increasing nitric oxide bioavailability. The endogenous CoQ10 synthesis is low in statin- treated patients, older people, septic patients, cardiovascular diseases, chronic kidney disease, people with diabetes and patients with critical illnesses. The covid19 causes severe inflammatory response and the patients with high inflammatory markers found to be low in CoQ-10.

How much Coenzyme Q-10 should I take?

Co enzyme-10 is a safe supplement, and the toxicity has not been reported in high oral intake. I do recommend taking Coenzyme Q10 up to 300 mg once a day for two weeks.

What are the side effects of Coenzyme Q-10?

There are no significant side effects to Coenzyme Q-10 other than minor diarrhoea nausea and heartburn at these dosages. It is not recommended to take if you are diagnosed with liver disease, during chemotherapy, nursing mothers.

Diabetic patients should monitor their blood sugar and should avoid if prone to have hypoglycaemic events.



What are the benefits of Bromelain?

Bromelain belongs to a group of enzymes found in the pineapple stem. Bromelain has anti- inflammatory, anti- edematous, and antithrombotic, activities, by reducing inflammatory markers after tissue injury. Bromelain is an excellent supplement to reduce pain, swelling, improve circulation and wound healing.

How much Bromelain should I take?

Bromelain has no known side effects and can take in very high doses, but I recommend to take 500mg four times a day.

What are the side effects of Bromelain?

There no known side effects of Bromelain.



Why should I have to take water?

The human body consists of 60% of water and helps to keep the body hydrated. Optimum hydration is essential because every cell in the human body needs to absorb nutrients and expel waste products. During an infection, the body will produce more waste products than usual. The hydration is necessary to maintain adequate urinary volume to eliminate the waste products and acids. You should drink enough water to keep sufficient urine volumes; this will reduce any risks of kidney stones. Nevertheless, kidney stones are not reported in the short term use of high doses of vitamin D. It is also essential to avoid the use of sugar and carbonated drinks during the infection as many are acidic and potentially cause the urine to become more acidic.

How much water should I take?

The usual advice is to take 6 to 8 mugs or at least one and a half litres of water a day. As all of us are different in body size and shape the good measure is to look into
the urine colour. Urine should be pale and should not irritate while peeing.



What activity should I do to prevent the complications of COVID19?

When you are sick, it is always good to have a good rest, but you should walk in the house without getting exhausted, or you can keep moving your arms & legs while laying.

Gentle deep breathing exercises regularly, you can take a deep breath, hold it a few seconds and let it go,

Blow a balloon if you are not allergic to latex

Sleep on your tummy a few times a day